Antidepressants: 4 Facts you should know.

antidepressants 3


This is a category of medicine or drug that helps to treat depression, seasonal affective disorder, dysthymia, social anxiety disorder, mild chronic depression, or other situations. Long-term usage of antidepressants causes side effects and other major diseases.


Selective Serotonin Reuptake Inhibitors

These are some of the commonly prescribed antidepressants as they have fewer side effects as compared to other antidepressants. 

Serotonin-norepinephrine Reuptake Inhibitors

This antidepressant is used to treat mood disorders, major depression, attention deficit hyperactivity, anxiety disorders, fibromyalgia, compulsive disorder, and more. 

As they treat major diseases, they also have many side effects, such as

  • Constipation
  • Diarrhea
  • Weight Loss
  • Tremor
  • Sedation
  • Insomnia
  • Anxiety
  • Lash

Tricyclic Antidepressants

These have been used since 1950 for treating depression. It works by growing norepinephrine levels in the brain and decreasing serotonin levels. Antihistamines and Anticholinergic are also TCA’s.

TCA’s also have the side effects that are listed below:-

  • Hypertension
  • Nausea
  • Vomiting
  • Anxiety
  • Seizures
  • Irregular heartbeat
  • Insomnia
  • Urinary retention
  • Abdominal cramps
  • Sexual dysfunction

Tetracyclic Antidepressants

It is used to treat a disorder as well as its symptoms. It treats symptoms such as low energy, sleeping trouble, nervousness, worthlessness, loss of pleasure, etc. 

These antidepressants are less used these days because of the invention of more powerful medicines. Also, they are least considered because of their side-effects. 


Moderate side effects

The side effects that affect our body moderately includes:-

  • Dry mouth
  • Nausea
  • Anxiety
  • Weight gain
  • Blurred vision
  • Sexual side effects
  • Constipation
  • Insomnia
  • Dizziness
  • Fatigue

Severe side effects

Although the severe side effects are rare, you should always be aware of them. Some of the severe side effects are listed below.

Serotonin Syndrome

It occurs when serotonin present in our brain attains a high level.

Its symptoms are muscle twitching, confusion, diarrhea, sweating, agitation, shivering, unconsciousness, high fever, seizures.


It is a condition the presence of salts or sodium in the blood decreases. That causes fluid to build up inside the body’s cells. The reason behind its side effects is hormonal imbalance due to disturbance in sodium or fluid level in your body. Its symptoms are

  • Confusion
  • Muscle pain
  • Headache
  • Feeling ill
  • Loss of appetite
  • Fatigue
  • Psychosis
  • Disorientation

Suicidal Thoughts

In the beginning, when you start consuming antidepressants, firstly, it will increase your depression and can cause thoughts of suicide to prevail in your brain. Its effects are worse in younger people as compared to elders or kids. If you or a person nearby you experiences such a condition, please seek medical assistance as soon as possible. 

Allergic Reactions

Antidepressants are made of many ingredients. Chances of allergy are high, as if the consumer would be allergic to any of the ingredients, they will face allergic reactions to the drug.

Its symptoms are itching, swelling, blisters, difficulty in breathing, hives, or many more. 


 Many times, when you take an antidepressant, you can experience mania. Maina is defined as mood swings. Its symptoms include irritability, racing thoughts, increased energy, extreme elevation of mood, problems in sleeping, pressured speech, etc.

Long term side effects

Although, antidepressants help you and make you less depressed. But, over a period of time, it has been observed that it does have some long-term side effects. The side effects observed are listed below. 

  • Feelings of emotional numbness
  • Reduced positivity
  • Reduce in the care about other people
  • They were not feeling like themselves.
  • Feeling of addiction
  • Lack of tolerance


Along with depression, antidepressants are used to treat many other diseases and disorders. The primary symptoms, disease, or disorder where antidepressants are being used are listed below.

  • Agitation
  • Obsessive-compulsive Disorder
  • Bedwetting
  • Bipolar Disorder
  • Anxiety Disorder
  • Migraine
  • Major Depressive Disorder
  • Posttraumatic Stress
  • Pain
  • Insomnia

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